MECHANICAL RING INTERFACES BETWEEN ADHERENS JUNCTION AND CONTRACTILE ACTOMYOSIN TO COORDINATE ENTOTIC CELL-IN-CELL FORMATION

Mechanical Ring Interfaces between Adherens Junction and Contractile Actomyosin to Coordinate Entotic Cell-in-Cell Formation

Summary: Entosis is a cell-in-cell (CIC)-mediated death program.Contractile actomyosin (CA) and the adherens junction (AJ) are two core elements essential for entotic CIC formation, but the molecular structures interfacing Ring Crimp Terminals them remain poorly understood.Here, we report the characterization of a ring-like structure interfacing be

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Post-ASPECTS based on hyperdensity in NCCT immediately after thrombectomy is an ultra-early predictor of hemorrhagic transformation and prognosis

Background and PurposeAlmost half of the patients exhibit futile recanalization after thrombectomy; however, the early postoperative predictors of futile recanalization remain unclear.We analyzed the relationship of post-thrombectomy ASPECTS (Post-ASPECTS) with 90-day prognosis and hemorrhagic transformation (HT).MethodsWe collected data from patie

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A pan-genome method to determine core regions of the Bacillus subtilis and Escherichia coli genomes [version 1; peer review: 2 approved]

Background: Synthetic engineering of bacteria to produce industrial products is a Pumps Water burgeoning field of research and application.In order to optimize genome design, designers need to understand which genes are essential, which are optimal for growth, and locations in the genome that will be tolerated by the organism when inserting enginee

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